Phenotypes Associated with This Genotype

Genotype
MGI:5301878

• Allelic Composition: Cd79a^tm1.1Cgn/Cd79a^tm1.1Cgn; Cd79b^tm1Gzmn/Cd79b^tm1Gzmn
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal B cell differentiation ( J:179254 )

• mice exhibit impaired pre-B and later stage B cell development unlike either single homozygote

increased pro-B cell number ( J:179254 )

decreased B cell number ( J:179254 )

• IgM+ B cells

absent pre-B cells ( J:179254 )

hematopoietic system

abnormal B cell differentiation ( J:179254 )

• mice exhibit impaired pre-B and later stage B cell development unlike either single homozygote

increased pro-B cell number ( J:179254 )

decreased B cell number ( J:179254 )

• IgM+ B cells

absent pre-B cells ( J:179254 )