Phenotypes Associated with This Genotype

Genotype
MGI:5301627

• Allelic Composition: Gt(ROSA)26Sor^{tm2(CAG-Notch2*)Uzs}/Gt(ROSA)26Sor⁺; Cd79a^tm1(cre)Reth/Cd79a⁺
• Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

arrested B cell differentiation ( J:179036 )

• B cell development is blocked at pro-B cell stage

decreased B cell number ( J:179036 )

• in the spleen, inguinal lymph nodes, and peritoneal cavity

increased T cell number ( J:179036 )

decreased splenocyte number ( J:179036 )

hematopoietic system

arrested B cell differentiation ( J:179036 )

• B cell development is blocked at pro-B cell stage

increased bone marrow cell number ( J:179036 )

• slightly

decreased B cell number ( J:179036 )

• in the spleen, inguinal lymph nodes, and peritoneal cavity

increased T cell number ( J:179036 )

decreased splenocyte number ( J:179036 )