neoplasm
• in all mice by 500 days
|
• development of palpable tumors in the mammary gland is delayed 3 to 4 months compared to in Ccnd1tm1Wbg/Ccnd1+ Tg(MMTV-PyVT)634Mul Tg(TetO-Ccnd1T286A)10897Kuw mice
• however, latency is the same as in Ccnd1tm1Wbg/Ccnd1tm1Wbg Tg(MMTV-PyVT)634Mul mice
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endocrine/exocrine glands
• in all mice by 500 days
|
integument
• in all mice by 500 days
|