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Phenotypes Associated with This Genotype
Genotype
MGI:5298854
Allelic
Composition		 C3tm1Crr/C3tm1Crr
Cd59atm1Bpm/Cd59atm1Bpm
Genetic
Background		 B6.129-Cd59atm1Bpm C3tm1Crr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
C3tm1Crr mutation (3 available); any C3 mutation (100 available)
Cd59atm1Bpm mutation (0 available); any Cd59a mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased T cell proliferation ( J:122201 )
• n CD4+ T cells stimulated with recombinant vaccinia virus glycoprotein 13 (p13) to the same extent as in Cd59atm1Bpm homozygotes

hematopoietic system
increased T cell proliferation ( J:122201 )
• n CD4+ T cells stimulated with recombinant vaccinia virus glycoprotein 13 (p13) to the same extent as in Cd59atm1Bpm homozygotes

cellular
increased T cell proliferation ( J:122201 )
• n CD4+ T cells stimulated with recombinant vaccinia virus glycoprotein 13 (p13) to the same extent as in Cd59atm1Bpm homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory