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Phenotypes Associated with This Genotype
Genotype
MGI:5297575
Allelic
Composition		 Myd88tm1Defr/Myd88tm1Defr
Tg(Vil1-cre)997Gum/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myd88tm1Defr mutation (4 available); any Myd88 mutation (50 available)
Tg(Vil1-cre)997Gum mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal gut flora balance ( J:177506 )
• mice exhibit a higher mucosal bacterial loads compared with Myd88tm1Defr control mice but not as much as in Myd88 null or conditionally knocked-out mice
• however, luminal bacterial loads are normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory