Phenotypes for Pax2 Pax8 MGI:5295945 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Pax2^tm1Mbu/Pax2⁺ Pax8^tm1(cre)Mbu/Pax8^tm1(cre)Mbu
Genetic Background	involves: 129P2/OlaHsd * C3H/He * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax2^tm1Mbu mutation (0 available); any Pax2 mutation (47 available)
Pax8^tm1(cre)Mbu mutation (0 available); any Pax8 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

absent metanephros ( J:80208 )

• mutant embryos fail to form a metanephros

• however, the adrenal gland, testis, and bladder develop normally

absent ureter ( J:80208 )

reproductive system

absent vas deferens ( J:80208 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/13/2026 MGI 6.24