Phenotypes for Cd19 Ptpn11 MGI:5295466 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cd19^tm1(cre)Cgn/Cd19⁺ Ptpn11^tm1Ckq/Ptpn11⁺
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19^tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
Ptpn11^tm1Ckq mutation (0 available); any Ptpn11 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:177285 )

neoplasm

increased acute lymphoblastic leukemia incidence ( J:177285 )

• B cell lymphoblastic leukemia/lymphoma in 4 of 9 mice

increased B cell derived lymphoma incidence ( J:177285 )

• B cell lymphoblastic leukemia/lymphoma in 4 of 9 mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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