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Phenotypes Associated with This Genotype
Genotype
MGI:5295296
Allelic
Composition		 Ube2btm1Jhjh/Ube2btm1Jhjh
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube2btm1Jhjh mutation (0 available); any Ube2b mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
impaired double-strand DNA break repair ( J:177475 )
• spermatocytes exhibit persistent double-strand DNA breaks in meiotic prophase unlike in wild-type cells

homeostasis/metabolism
impaired double-strand DNA break repair ( J:177475 )
• spermatocytes exhibit persistent double-strand DNA breaks in meiotic prophase unlike in wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory