Phenotypes for Mybl1 MGI:5292391 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mybl1^repro9/Mybl1^tm1Epr
Genetic Background	involves: C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mybl1^repro9 mutation (1 available); any Mybl1 mutation (33 available)
Mybl1^tm1Epr mutation (1 available); any Mybl1 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

azoospermia ( J:175539 )

• mice lack postmeiotic spermatids

arrest of male meiosis ( J:175539 )

• before the mid-pachytene transition

abnormal synaptonemal complex ( J:175539 )

• some spermatocytes fail to establish or maintain synapsis of homologous autosomes

abnormal testis morphology ( J:175539 )

• some spermatocytes fail to establish or maintain synapsis of homologous autosomes

male infertility ( J:175539 )

endocrine/exocrine glands

abnormal testis morphology ( J:175539 )

• some spermatocytes fail to establish or maintain synapsis of homologous autosomes

cellular

azoospermia ( J:175539 )

• mice lack postmeiotic spermatids

arrest of male meiosis ( J:175539 )

• before the mid-pachytene transition

abnormal synaptonemal complex ( J:175539 )

• some spermatocytes fail to establish or maintain synapsis of homologous autosomes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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