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Phenotypes Associated with This Genotype
Genotype
MGI:5286097
Allelic
Composition
Tg(GFAP-Hras1)2Agu/Tg(GFAP-Hras1)2Agu
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice begin to die at 2 months of age
• 50% of mice die by 3 months of age
• mice die by 4 to 6 months of age

nervous system
• at 3 weeks with trisomies
• mild, widespread astrocytic hyperplasia

neoplasm
• at 3 weeks with trisomies

behavior/neurological

cellular
• 88% of astrocytoma cells exhibit trisomies

growth/size/body

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
high grade glioma DOID:3070 OMIM:PS137800
J:69129
malignant astrocytoma DOID:3069 J:69129


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/09/2022
MGI 6.21
The Jackson Laboratory