Mouse Genome Informatics
hm
    Cplx2tm1Rmnd/Cplx2tm1Rmnd
B6NCrl.Cg-Cplx2tm1Rmnd
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
N
• independent of parietal cortical neurotrauma, mice exhibit normal social interaction, sucrose preference test for anhedonia, forced alternation in a T-maze, novel object recognition, and pre-pulse inhibition (J:175056)
• independent of parietal cortical neurotrauma, mice spend less time in the center and intermediate area with increased time in the periphery of an open field compared with similarly treated wild-type mice
• however, mice exhibit normal anxiety-related behaviors in an elevated plus maze
• in a Morris water maze, independent of parietal cortical neurotrauma
• in a Morris water maze, mice subjected to parietal cortical neurotrauma exhibit increased latency to escape by trial 6 through 8 compared with similarly treated wild-type mice
• following parietal cortical neurotrauma
• in mice subjected to parietal cortical neurotrauma
• on a rotarod, independent of parietal cortical neurotrauma
• MK-801-treated mice subjected to parietal cortical neurotrauma exhibit increased hyperlocomotion compared with similarly treated wild-type mice
• in an open field, independent of parietal cortical neurotrauma

nervous system
• reduced volume following parietal cortical neurotrauma

Mouse Models of Human Disease
OMIM IDRef(s)
Schizophrenia; SCZD 181500 J:175056