Phenotypes for Egfr Fos Tg(KRT5-SOS1)892A6Wag MGI:5142271 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Egfr^wa2/Egfr⁺ Fos^{tm2(Fosl1)Wag}/Fos^{tm2(Fosl1)Wag} Tg(KRT5-SOS1)892A6Wag/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egfr^wa2 mutation (2 available); any Egfr mutation (87 available)
Fos^{tm2(Fosl1)Wag} mutation (0 available); any Fos mutation (43 available)
Tg(KRT5-SOS1)892A6Wag mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased skin papilloma incidence ( J:175064 )

decreased tumor growth/size ( J:175064 )

• tumor burden is reduced compared to in Tg(KRT5-SOS1)892A6Mka mice

integument

increased skin papilloma incidence ( J:175064 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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