Phenotypes for Rag2 Unc93b1 MGI:5140973 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rag2^tm1Fwa/Rag2^tm1Fwa Unc93b1^tm1.1Kmiy/Unc93b1^tm1.1Kmiy
Genetic Background	involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag2^tm1Fwa mutation (45 available); any Rag2 mutation (115 available)
Unc93b1^tm1.1Kmiy mutation (6 available); any Unc93b1 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:174308 )

N	• unlike Unc93b1^tm1.1Kmiy homozygotes, mice do not exhibit premature death

hematopoietic system

hematopoietic system phenotype ( J:174308 )

N	• platelet counts are the same as in Rag2^tm1Fwa homozygotes • unlike in Unc93b1^tm1.1Kmiy homozygotes, spleen size is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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