Phenotypes Associated with This Genotype

Genotype
MGI:5049889

• Allelic Composition: Porcn^tm1.1Lcm/Y; Tg(Msx2-cre)5Rem/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Tissue-specific Porcn^tm1.1Lcm deletion phenotypes include skeletal defects and skin abnormalities

limbs/digits/tail

decreased autopod size ( J:173672 )

♂ • truncated

syndactyly ( J:173672 )

♂

integument

abnormal skin morphology ( J:173672 )

♂ • at E18.5, mice exhibit focal and dermis defects compared with wild-type mice

abnormal dermal layer morphology ( J:173672 )

♂ • at E18.5