Phenotypes for Cd40 MGI:5013462 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Cd40^tm1Kik/Cd40^tm1Kik
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd40^tm1Kik mutation (11 available); any Cd40 mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:173115 )

N	• mice exhibit well-developed thymic medullas

decreased B cell number ( J:190943 )

• NP-CG immunized mice fail to generate NP-specific IgG1+B cells at day 7

absent germinal center B cells ( J:190943 )

• NP-CG immunized mice fail to generate NP-specific germinal center B cells

hematopoietic system

decreased B cell number ( J:190943 )

• NP-CG immunized mice fail to generate NP-specific IgG1+B cells at day 7

absent germinal center B cells ( J:190943 )

• NP-CG immunized mice fail to generate NP-specific germinal center B cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/28/2026 MGI 6.24