Analysis Tools
vision/eye
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• at P20, optic nerves exhibit disordered lamination in the direct circumference compared to in wild-type mice
• however, lamination in the periphery is normal
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• at P180
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• with rossette formation
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• degeneration
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• in all mice
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• at P180 near the optic nerve and scattered in the posterior part of the eye in 80% of mice
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• at P30, a-wave and b-wave amplitudes are smaller at higher light intensities compared with wild-type mice
• at P30 and P180, the ratio between the amplitudes of oscillatory potentials and b-waves is higher than in wild-type mice
• at P180, electroretinogram waveforms and parameters are different than in wild-type mice
• at P180, the b/a ratio is decreased compared to in wild-type mice
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• at P30 and P180, photopic b-wave and photopic 30 Hz flicker amplitudes are smaller than in wild-type mice
• at P180, scotopic and photopic oscillatory potential amplitudes are smaller than in wild-type mice
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• at P30, mice exhibit reduced amplitudes compared with wild-type mice
• at P180, scotopic a-wave and b-wave amplitudes are smaller than in wild-type mice
• at P180, scotopic and photopic oscillatory potential amplitudes are smaller than in wild-type mice
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pigmentation
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• in the eye at P180
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growth/size/body
cardiovascular system
nervous system
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• with rossette formation
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• at P20, optic nerves exhibit disordered lamination in the direct circumference compared to in wild-type mice
• however, lamination in the periphery is normal
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