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Phenotypes Associated with This Genotype
Genotype
MGI:5003063
Allelic
Composition
Anp32btm1Mak/Anp32btm1Mak
Genetic
Background
B6.129P2-Anp32btm1Mak
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32btm1Mak mutation (1 available); any Anp32b mutation (101 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most mice die between E17.5 and the first 12 hours after birth
• Background Sensitivity: more mice die on a congenic C57BL/6 background compared with mice on a mixed background
• however, mice that are detected at 12 hours exhibit normal survival to adulthood

craniofacial
• some mice exhibit palate closure defect compared with wild-type mice

nervous system
• some mice exhibit overlarge brain ventricles compared with wild-type mice

respiratory system
• some mice never initiate breathing

hearing/vestibular/ear
• some mice exhibit expanded inner ear cavities compared with wild-type mice

digestive/alimentary system
• some mice exhibit palate closure defect compared with wild-type mice

growth/size/body
• some mice exhibit palate closure defect compared with wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory