Phenotypes for Ppp2r5d Tg(Thy1-MAPT)5Vln MGI:4950910 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ppp2r5d^tm1Vjan/Ppp2r5d^tm1Vjan Tg(Thy1-MAPT)5Vln/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp2r5d^tm1Vjan mutation (0 available); any Ppp2r5d mutation (34 available)
Tg(Thy1-MAPT)5Vln mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal behavior ( J:171339 )

• mice take more time to remove an adhesive sticker than Tg(Thy1-MAPT)5Vln mice

impaired coordination ( J:171339 )

• in beam walk and rotatrod tests to a greater extent than in either Ppp2r5d^tm1Vjan homozygotes or Tg(Thy1-MAPT)5Vln mice

decreased thermal nociceptive threshold ( J:171339 )

• compared with Tg(Thy1-MAPT)5Vln mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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