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Phenotypes Associated with This Genotype
Genotype
MGI:4950287
Allelic
Composition		 Tlr5tm1Flv/Tlr5tm1Flv
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tlr5tm1Flv mutation (2 available); any Tlr5 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal leukocyte migration ( J:171379 )
• flagellin-treated mice exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice

cellular
abnormal leukocyte migration ( J:171379 )
• flagellin-treated mice exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice

hematopoietic system
abnormal leukocyte migration ( J:171379 )
• flagellin-treated mice exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory