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Phenotypes Associated with This Genotype
Genotype
MGI:4950264
Allelic
Composition		 Gnas/Nespastm1.1Jop/Gnas+
Genetic
Background		 involves: 129S1/Sv * M. spretus
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gnas/Nespastm1.1Jop mutation (0 available); any Gnas mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal DNA methylation ( J:171195 )
• when this allele is inherited maternally, some mice exhibit loss of methylation of Nespas differentially methylated region (DMR) compared with wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory