Phenotypes Associated with This Genotype

Genotype
MGI:4948512

• Allelic Composition: Rr117^tm1.1Dje/Rr117⁺; Shh^tm1Amc/Shh⁺
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:170540 )

• 80% of mice fail to gain weight and die by 7 days of age

• 20% survive to adulthood

growth/size/body

slow postnatal weight gain ( J:170540 )

• normal weight at birth

• 80% fail to gain weight after birth and die by 7 days of age

• the 20% who survive remain remain small, 33% of normal weight

behavior/neurological

behavior/neurological phenotype ( J:170540 )

N • normal suckling response

N • dead pups often have milk in their stomach

N • well coordinated motor control

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:170540 )

N • normal blood glucose