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Phenotypes Associated with This Genotype
Genotype
MGI:4947650
Allelic
Composition		 En1tm1(Tnf)Fpit/En1tm1(Tnf)Fpit
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1tm1(Tnf)Fpit mutation (0 available); any En1 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased physiological sensitivity to xenobiotic ( J:170743 )
• mice exhibit neuroprotection against 6-OHDA injection compared with wild-type mice

nervous system
nervous system phenotype ( J:170743 )
N
• dopaminergic neuron viability is normal
• mice do not exhibit inflammatory infiltration or microglia activation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory