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Phenotypes Associated with This Genotype
Genotype
MGI:4943702
Allelic
Composition		 Errfi1tm1Jwj/Errfi1tm1Jwj
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Errfi1tm1Jwj mutation (0 available); any Errfi1 mutation (15 available)
Gt(ROSA)26Sortm1(cre/ERT2)Thl mutation (0 available); any Gt(ROSA)26Sor mutation (1062 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
respiratory system phenotype ( J:153715 )
N
• following tamoxifen treatment, mice display normal alveolar spaces and normal lung structure with no detectable mucosal cells
• expression of key lung molecular markers remains normal in adult lungs

reproductive system
uterus hyperplasia ( J:153715 )
• following tamoxifen treatment, mice display uterine hyperplasia

integument
increased skin papilloma incidence ( J:153715 )
• following tamoxifen treatment, mice display dermal papillomas

neoplasm
increased skin papilloma incidence ( J:153715 )
• following tamoxifen treatment, mice display dermal papillomas

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory