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Phenotypes Associated with This Genotype
Genotype
MGI:4943546
Allelic
Composition		 Ptentm1Hwu/Ptentm1Hwu
Tg(Cdh16-cre)91Igr/0
Genetic
Background		 involves: 129S4/SvJae * BALB/c * C57BL/6J * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1Hwu mutation (17 available); any Pten mutation (86 available)
Tg(Cdh16-cre)91Igr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal/urinary system phenotype ( J:137073 )
N
• mutants do not develop hydronephrosis
abnormal ureter morphology ( J:137073 )
• hyperproliferation and enlarged epithelial cells in the ureter
abnormal urinary bladder urothelium morphology ( J:137073 )
• hyperproliferation and enlarged epithelial cells in the bladder

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory