Phenotypes Associated with This Genotype

Genotype
MGI:4943279

• Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor; Tg(Pax6-cre,GFP)1Pgr/0
• Genetic Background: involves: 129X1/SvJ * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal lacrimal gland development ( J:130571 )

• at E14.5, the presumptive lacrimal gland precursor remains a thin layer of epithelial cells with little proliferation and no budding unlike in wild-type mice

absent lacrimal gland bud ( J:130571 )

• at E14.5, mutants never develop lacrimal buds

absent lacrimal glands ( J:130571 )

vision/eye

abnormal lacrimal gland development ( J:130571 )

• at E14.5, the presumptive lacrimal gland precursor remains a thin layer of epithelial cells with little proliferation and no budding unlike in wild-type mice

absent lacrimal gland bud ( J:130571 )

• at E14.5, mutants never develop lacrimal buds

absent lacrimal glands ( J:130571 )