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Phenotypes Associated with This Genotype
Genotype
MGI:4943267
Allelic
Composition		 Apctm1Tno/Apctm1Tno
Ptentm1Hwu/Ptentm1Hwu
Tg(Cyp1a1-cre/ERT)1Dwi/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Tno mutation (5 available); any Apc mutation (156 available)
Ptentm1Hwu mutation (17 available); any Pten mutation (87 available)
Tg(Cyp1a1-cre/ERT)1Dwi mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal urinary bladder urothelium morphology ( J:164579 )
• mice develop hyperplastic lesions in the bladder unlike wild-type mice that are larger than in Apctm1Tno/Apctm1Tno Tg(Cyp1a1-cre/ERT)1Dwi mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory