Phenotypes for Gt(ROSA)26Sor Hand2 Isl1 MGI:4940091 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hand2^tm1Dsr/Hand2^tm2.1Dsr Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Isl1^tm1(cre)Tmj/Isl1⁺
Genetic Background	involves: 129S4/SvJaeSor * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1060 available)
Hand2^tm1Dsr mutation (0 available); any Hand2 mutation (14 available)
Hand2^tm2.1Dsr mutation (0 available); any Hand2 mutation (14 available)
Isl1^tm1(cre)Tmj mutation (0 available); any Isl1 mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal heart development ( J:169213 )

• at E9.5, mice exhibit fewer progenitor cells migration into the outflow tract compared with control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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