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Phenotypes Associated with This Genotype
Genotype
MGI:4939793
Allelic
Composition
Nlrc5tm1Aki/Nlrc5tm1Aki
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrc5tm1Aki mutation (0 available); any Nlrc5 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• mice exhibit normal inflammatory cytokine and type I IFN production in response to stimulation with agonists for Toll-like receptor, RIG-I-like receptor, and a DNA sensor
• mice exhibit normal IL1b production after stimulation or infection with NLRP3 and AIM2 activators or bacteria


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory