Phenotypes for Rb1cc1 Tg(Mx1-cre)1Cgn MGI:4936844 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rb1cc1^tm1.1Guan/Rb1cc1^tm1.1Guan Tg(Mx1-cre)1Cgn/0
Genetic Background	B6.Cg-Rb1cc1^tm1.1Guan Tg(Mx1-cre)1Cgn

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1cc1^tm1.1Guan mutation (0 available); any Rb1cc1 mutation (85 available)
Tg(Mx1-cre)1Cgn mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal hematopoietic stem cell morphology ( J:167258 )

• fetal hemoatopoietic stem cells (HSC) are unable to reconstitute lethally irradiated recipients after pIpC treatment to induce cre expression, indicating cell-autonomous requirement for maintanance and function of fetal HSCs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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