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Phenotypes Associated with This Genotype
Genotype
MGI:4889121
Allelic
Composition		 Pygo2tm1.2Xdai/Pygo2tm1.2Xdai
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pygo2tm1.2Xdai mutation (0 available); any Pygo2 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
decreased mammary gland epithelial cell proliferation ( J:163218 )
• mammary buds from embryos exhibit reduced proliferation with impaired cell cycle progression compared with cells from wild-type mice

integument
decreased mammary gland epithelial cell proliferation ( J:163218 )
• mammary buds from embryos exhibit reduced proliferation with impaired cell cycle progression compared with cells from wild-type mice

cellular
decreased mammary gland epithelial cell proliferation ( J:163218 )
• mammary buds from embryos exhibit reduced proliferation with impaired cell cycle progression compared with cells from wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory