About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4887828
Allelic
Composition		 Slc17a6tm1Kldr/Slc17a6tm1Kldr
Tg(Trpv1-icre)1Kldr/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc17a6tm1Kldr mutation (1 available); any Slc17a6 mutation (60 available)
Tg(Trpv1-icre)1Kldr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
excessive scratching ( J:167752 )
• scratching behavior is significantly elevated compared to controls
increased thermal nociceptive threshold ( J:167752 )
• mice show decreased thermal pain sensitivity, but mechanical pain and inflammatory pain sensitivities are not different from control

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory