Phenotypes Associated with This Genotype

Genotype
MGI:4868751

• Allelic Composition: Fto^tm1.1Pzg/Fto^tm1.1Pzg; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased lean body mass ( J:166984 )

decreased body length ( J:166984 )

postnatal growth retardation ( J:166984 )

homeostasis/metabolism

decreased circulating insulin-like growth factor I level ( J:166984 )

abnormal carbon dioxide production ( J:166984 )

• relative to lean mass, mice exhibit increased oxygen consumption and carbon dioxide production compared with wild-type mice

abnormal oxygen consumption ( J:166984 )

• relative to lean mass, mice exhibit increased oxygen consumption and carbon dioxide production compared with wild-type mice

behavior/neurological

abnormal eating behavior ( J:166984 )

• when normalized to lean mass

skeleton

decreased bone mineral density ( J:166984 )