Phenotypes Associated with This Genotype

Genotype
MGI:4867649

• Allelic Composition: Lta/Tnf^tm1Eug/Lta/Tnf^tm1Eug
• Genetic Background: involves: 129 * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased heart weight ( J:112797 )

• when fed a high cholesterol diet

increased body mass index ( J:112797 )

• when fed a high cholesterol diet

increased body weight ( J:112797 )

• whether fed standard chow or a high cholesterol diet

increased body length ( J:112797 )

• when fed a high cholesterol diet

increased susceptibility to diet-induced obesity ( J:112797 )

• when fed a high cholesterol diet

enlarged liver ( J:112797 )

• after 12 weeks on a high cholesterol diet

increased liver weight ( J:112797 )

• after 12 weeks on a high cholesterol diet

increased spleen weight ( J:112797 )

• when fed a high cholesterol diet

liver/biliary system

enlarged liver ( J:112797 )

• after 12 weeks on a high cholesterol diet

increased liver weight ( J:112797 )

• after 12 weeks on a high cholesterol diet

hepatic steatosis ( J:112797 )

• after 12 weeks on a high cholesterol diet

skeleton

long tibia ( J:112797 )

• when fed a high cholesterol diet

cardiovascular system

increased heart weight ( J:112797 )

• when fed a high cholesterol diet

homeostasis/metabolism

increased susceptibility to diet-induced obesity ( J:112797 )

• when fed a high cholesterol diet

immune system

increased spleen weight ( J:112797 )

• when fed a high cholesterol diet

limbs/digits/tail

long tibia ( J:112797 )

• when fed a high cholesterol diet

hematopoietic system

increased spleen weight ( J:112797 )

• when fed a high cholesterol diet