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Phenotypes Associated with This Genotype
Genotype
MGI:4843115
Allelic
Composition		 Adarb1tm1.1Skwa/Adarb1tm1.1Skwa
Gria2tm1.1Phs/Gria2tm1.1Phs
Tg(SLC18A3-cre)KMisa/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adarb1tm1.1Skwa mutation (0 available); any Adarb1 mutation (39 available)
Gria2tm1.1Phs mutation (2 available); any Gria2 mutation (78 available)
Tg(SLC18A3-cre)KMisa mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:164294 )
N
• mice exhibit normal motor function until 6 months of age

nervous system
nervous system phenotype ( J:164294 )
N
• motor neuron death observed in Adarb1tm1.1Skwa/Adarb1tm1.1Skwa Tg(SLC18A3-cre)KMisa mice is prevented

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory