Phenotypes for Gt(ROSA)26Sor TgTn(pb-sb-ATP2)H27Brd MGI:4840558 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)H27Brd/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1(pb)Peli mutation (0 available); any Gt(ROSA)26Sor mutation (944 available)
TgTn(pb-sb-ATP2)H27Brd mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:166063 )

neoplasm

abnormal tumor susceptibility ( J:166063 )

• develop primarily hematopoietic tumors

increased leukemia incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

increased lymphoma incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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