Phenotypes for Adgra2 Tg(Tek-cre)12Flv MGI:4840270 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Adgra2^tm1Cjku/Adgra2^tm2Cjku Tg(Tek-cre)12Flv/0
Genetic Background	involves: 129/Sv * C3H * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgra2^tm1Cjku mutation (0 available); any Adgra2 mutation (43 available)
Adgra2^tm2Cjku mutation (0 available); any Adgra2 mutation (43 available)
Tg(Tek-cre)12Flv mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:166127 )

• basally localized glomeruloid malformations in hemorrhagic areas of the CNS

internal hemorrhage ( J:166127 )

• stated to be identical to the phenotype seen in mice homozygous for Gpr124^tm1Cjku

• forebrain hemorrhage

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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