Phenotypes Associated with This Genotype

Genotype
MGI:4839499

• Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu; Tg(Cdh16-cre)91Igr/0
• Genetic Background: involves: 129S4/SvJae * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:137442 )

♂ • epithelial hyperplasia in vesicular glands

reproductive system

abnormal reproductive system morphology ( J:137442 )

• genital tissues are enlarged

abnormal seminal vesicle morphology ( J:137442 )

♂ • epithelial hyperplasia in vesicular glands

abnormal endometrium morphology ( J:137442 )

♀ • endometrial hyperplasia is accompanied by partial squamous differentiation

endometrium hyperplasia ( J:137442 )

♀ • hyperplasia of the endometrial glands and lumen

abnormal epididymis epithelium morphology ( J:137442 )

♂ • epithelial hyperplasia in epididymis

abnormal vas deferens morphology ( J:137442 )

♂ • epithelial hyperplasia in vas deferens

neoplasm

neoplasm ( J:137442 )

N • mice up to 1 year of age do not form tumors