Phenotypes Associated with This Genotype

Genotype
MGI:4839179

• Allelic Composition: Tox^tm1Kay/Tox^tm1Kay; Tg(Lck-cre)1Cwi/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal CD4-positive T cell differentiation ( J:164687 )

• the T cell defect seen in germline null mice is recapitulated in these mice

• however, all lymph nodes are present

hematopoietic system

abnormal CD4-positive T cell differentiation ( J:164687 )

• the T cell defect seen in germline null mice is recapitulated in these mice

• however, all lymph nodes are present