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Phenotypes Associated with This Genotype
Genotype
MGI:4839048
Allelic
Composition		 Il10tm1Cgn/Il10tm1Cgn
Genetic
Background		 B10.129P2(B6)-Il10tm1Cgn/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il10tm1Cgn mutation (15 available); any Il10 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased length of allograft survival ( J:44346 )
• decrease in survival times of heart transplants from BALB/c mice after a 30 day course of anti-CD4 and anti-CD8 mAb
• acute rejection severity of cardiac allografts (BALB/c) is increased compared to wild-type controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory