nervous system
• mice treated with tamoxifen to induce cre-recombination exhibit an increase in white matter volume
|
• many axons in the corpus callosum are hypermyelinated when mice are treated with tamoxifen to induce cre-recombination
|
• increase in myelin sheath thickness
• outfoldings of the myelin sheaths in CNS and PNS are observed
|
• axons in the optic nerve are hypermyelinated when mice are treated with tamoxifen to induce cre-recombination
|
• many axons in the corpus callosum and optic nerve are hypermyelinated when mice are treated with tamoxifen to induce cre-recombination
• normally nonmyelinated C-fiber axons are spirally enwrapped by Remak Schwann cells are seen in mice treated with tamoxifen to induce cre-recombination
|
vision/eye
• axons in the optic nerve are hypermyelinated when mice are treated with tamoxifen to induce cre-recombination
|