Phenotypes Associated with This Genotype

Genotype
MGI:4831157

• Allelic Composition: Tg(SOD1*G93A)1Gur/0; Vegfa^tm2Pec/Vegfa^tm2Pec
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:84843 )

• die earlier (107 3 d) than Tg(SOD1*G93A)1Gur mice

muscle

muscle weakness ( J:84843 )

• worse muscle weakness than Tg(SOD1*G93A)1Gur mice

behavior/neurological

impaired coordination ( J:84843 )

• perform worse in the rotarod test (unable to stay for 2 min on the rotarod beyond 98 2 d) than Tg(SOD1*G93A)1Gur mice