Phenotypes for Actb Insr Tg(Hsp70-1-cre)6Arge MGI:4831153 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Actb^tm1(INSR)Dac/Actb^tm1(INSR)Dac Insr^tm1Dac/Insr^tm1Dac Tg(Hsp70-1-cre)6Arge/?
Genetic Background	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Actb^tm1(INSR)Dac mutation (0 available); any Actb mutation (51 available)
Insr^tm1Dac mutation (2 available); any Insr mutation (94 available)
Tg(Hsp70-1-cre)6Arge mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:91350 )

• die between 6 and 8 weeks

homeostasis/metabolism

increased circulating glucose level ( J:91350 )

• diabetic in one week

increased circulating insulin level ( J:91350 )

• extremely elevated

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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