Phenotypes Associated with This Genotype

Genotype
MGI:4821398

• Allelic Composition: Egr1^tm1Jmi/Egr1^tm1Jmi; Tg(Scgb1a1-rtTA,-tTS,tetO-TGFB1*)1Eli/?
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

respiratory system

respiratory system phenotype ( J:92469 )

N • early apoptosis is not observed

lung inflammation ( J:92469 )

• inflammation occurs but with moderately reduced inflammatory cell accumulation relative to controls carrying only the transgene

abnormal pulmonary alveolus morphology ( J:92469 )

• alveolar remodeling is diminished

pulmonary fibrosis ( J:92469 )

• fibrosis response is reduced

immune system

lung inflammation ( J:92469 )

• inflammation occurs but with moderately reduced inflammatory cell accumulation relative to controls carrying only the transgene