Analysis Tools
respiratory system
|
• inflammatory response evident in lungs after 2 days of dox treatment and increases for 10 days
• increased myocytes and myofibroblasts by 10 days of dox treatment
|
|
• apoptosis is increased 12 hours after dox induction
• apoptosis peaks at 48 hours and then disappears
|
|
• alveolar remodeling
|
|
• airway and parenchymal fibrotic response by 2 days after dox treatment
• fibrotic response of alveolar perenchyma develops later
• lung collagen content is increased after 2 months of dox treatment
|
immune system
|
• inflammatory response evident in lungs after 2 days of dox treatment and increases for 10 days
• increased myocytes and myofibroblasts by 10 days of dox treatment
|
