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Phenotypes Associated with This Genotype
Genotype
MGI:4821325
Allelic
Composition		 Flt4tm1.1Ichi/Flt4+
Krastm1Mok/Kras+
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flt4tm1.1Ichi mutation (0 available); any Flt4 mutation (77 available)
Krastm1Mok mutation (6 available); any Kras mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
lymphedema ( J:159024 )
• intestinal
chylous ascites ( J:159024 )
• all mice develop chylous ascites unlike wild-type mice

immune system
lymphatic vessel hypoplasia ( J:159024 )
• mice develop lymphatic vessel hypoplasia unlike wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory