Phenotypes for Nf2 Tg(Nes-cre)1Kln MGI:4819847 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nf2^tm2Gth/Nf2^tm2Gth Tg(Nes-cre)1Kln/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nf2^tm2Gth mutation (3 available); any Nf2 mutation (67 available)
Tg(Nes-cre)1Kln mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal lens morphology ( J:162628 )

• ectopic cells accumulate in the equator and posterior of the lens unlike in wild-type mice

abnormal lens epithelium morphology ( J:162628 )

• in the anterior region

cataract ( J:162628 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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