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Phenotypes Associated with This Genotype
Genotype
MGI:4819230
Allelic
Composition
Ikzf1tm1Kast/Ikzf1+
Tg(BCR/ABL)623Hkp/0
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ikzf1tm1Kast mutation (0 available); any Ikzf1 mutation (5 available)
Tg(BCR/ABL)623Hkp mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mice develop B cell acute lymphoblastic leukemia with a median latency of 5.7 weeks

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
acute lymphocytic leukemia DOID:9952 OMIM:247640
OMIM:613065
OMIM:613067
OMIM:615545
J:160846


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory