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Phenotypes Associated with This Genotype
Genotype
MGI:4819230
Allelic
Composition		 Ikzf1tm1Kast/Ikzf1+
Tg(BCR/ABL)623Hkp/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ikzf1tm1Kast mutation (0 available); any Ikzf1 mutation (30 available)
Tg(BCR/ABL)623Hkp mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased acute lymphoblastic leukemia incidence ( J:160846 )
• mice develop B cell acute lymphoblastic leukemia with a median latency of 5.7 weeks

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
acute lymphoblastic leukemia DOID:9952 OMIM:247640
OMIM:613065
 J:160846

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory