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Phenotypes Associated with This Genotype
Genotype
MGI:4819172
Allelic
Composition
Tg(Lck-LMO1)11Sjk/0
Tg(STIL-TAL1)A5(3)Alpa/0
Genetic
Background
involves: C3H * C3H/HeRos * C57BL/6 * C57BL/10Ros
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• lymphoblasts replace bone marrow

neoplasm
• 95% of mice develop aggressive T cell leukemia/lymphomas within 6 months
• 95% of mice develop aggressive T cell leukemia/lymphomas within 6 months

behavior/neurological

liver/biliary system

respiratory system

immune system
• peripheral
• mice exhibit widespread organ infiltration including liver, kidney, lung, and bone marrow

endocrine/exocrine glands
• 95% of mice develop aggressive T cell leukemia/lymphomas within 6 months

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
acute lymphocytic leukemia DOID:9952 OMIM:247640
OMIM:613065
OMIM:613067
OMIM:615545
J:40868


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory