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Phenotypes Associated with This Genotype
Genotype
MGI:4819098
Allelic
Composition
Nogtm1Amc/Nogtm1Amc
Smad3tm1Xfw/Smad3+
Genetic
Background
involves: 129/Sv * 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nogtm1Amc mutation (2 available); any Nog mutation (8 available)
Smad3tm1Xfw mutation (0 available); any Smad3 mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• in 29% of mice (J:161524)
• in 29% of mice (J:161524)

embryogenesis
• expression analysis indicates a defect in anterior primitive streak development (J:161524)
• expression analysis indicates a defect in anterior primitive streak development (J:161524)
• expression analysis indicates defects in patterning and function (J:161524)
• expression analysis indicates defects in patterning and function (J:161524)
• 29% (17 of 58) show defects in anterior midline tissues (J:161524)
• 29% (17 of 58) show defects in anterior midline tissues (J:161524)
• expression analysis indicates defects in patterning and function in the anterior most axial mesendoderm (J:161524)
• expression analysis indicates defects in patterning and function in the anterior most axial mesendoderm (J:161524)
• expression analysis indicates impairment in ADE specification (J:161524)
• expression analysis indicates impairment in ADE specification (J:161524)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory