Mouse Genome Informatics
cx
    Nogtm1Amc/Nogtm1Amc
Smad3tm1Xfw/Smad3+

involves: 129/Sv * 129S1/Sv
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• in 29% of mice

embryogenesis
• expression analysis indicates a defect in anterior primitive streak development
• expression analysis indicates defects in patterning and function
• 29% (17 of 58) show defects in anterior midline tissues
• expression analysis indicates defects in patterning and function in the anterior most axial mesendoderm
• expression analysis indicates impairment in ADE specification