Phenotypes Associated with This Genotype

Genotype
MGI:4818571

• Allelic Composition: Lmx1b^tm1Rjo/Lmx1b^tm4.1Rjo; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * CBA/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

ciliary body hypoplasia ( J:161793 )

• hypoplastic at E18.5

iris stroma hypoplasia ( J:161793 )

• at E18.5

irregularly shaped pupil ( J:161793 )

• at E18.5

• less severe than in Lmxb1^tm1Rjo homozygous mice

abnormal cornea morphology ( J:161793 )

cornea vascularization ( J:161793 )

• blood vessels are present in the corneal stroma

abnormal cornea stroma morphology ( J:161793 )

• less dense

• blood vessels are present

decreased eye anterior chamber depth ( J:161793 )

• decrease in anterior chamber depth

abnormal lens epithelium morphology ( J:161793 )

• thickened

microphthalmia ( J:161793 )

• at E18.5

cardiovascular system

cornea vascularization ( J:161793 )

• blood vessels are present in the corneal stroma